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Displaying 1 - 10 of 11 results.

Lassa Fever: a rodent-human interaction

This resource examines the sites of interactions between humans and the multimammate mouse, Mastomys natalensis. It presents findings such as new arenaviruses in other African rodents and in snakes, that  argue preferably toward the host-switching concept. The recent emergence in Sierra Leone, the absence of virus positive Mastomys between the two endemic zones and poor virus diversity in the Mano River area also point in the direction of a unique import of Lassa virus from Nigeria to Sierra Leone during the 19th century. This resource also discusses the hypothesis of human displacements through the Atlantic slave trade and its abolition in 1807.

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Diversity and dynamics in a community of small mammals in coastal Guinea, West Africa

This resource investigated three villages in high endemic zones of Lassa fever in Guinea and presents the biodeiversity of the small mammal community identified through standardized trapping in houses, cultivations and forest.

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Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. The study highlights that further research is necessary to identify the mechanism and the epidemiology of LF-induced SNHL.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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Housing factors and transmission of Lassa fever in a rural area of South-South Nigeria

The study compared the housing quality and hygiene in two peri-urban settlements in Irrua Town. The use of buildings for housing and commercial activities was found to be a risk for the transmission of Lassa fever in the houses.

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Dealing with the unseen: Ffear and stigma in Lassa fever

This poster reports on research carried out with patients and caregivers at Irrua hospital.  It shows how many patients feared telling their family members that they were infected with Lassa Fever, and some were rejected by their family who refused to care for them.

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Understanding the cryptic nature of Lassa fever in West Africa

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden.

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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: The case of Lassa fever

The authors present the results of a modelling approach, using published data from outbreak and patients to Kenema governmental Hospital in Sierra Leone. They estimate the likely contribution to human to human transmission. They shed light on the need to better assess the human to human transmission.

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Fluctuation of abundance and Lassa virus prevalence in Mastomys Natalensis in Guinea, West Africa

This study investigates the link between the ecology of the M. Natalensis and the incidence of Lassa fever in human cases in Guinea. They found that the risk for Lassa virus transmission was present in both rainy and dry season; however the risk increased in the dry season because of the possibility of encountering rodent excreta in the houses.

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Impact of Lassa fever on the practice and consumption of stored food by University of Benin community, in Benin City, Nigeria

The aim of the study is to determine the impact of Lassa fever on the consumption of processed snacks and food storage practices in University of Benin campuses. They found that the that majority discard their snacks when contaminated while some remove the contaminated portions and consume remaining part which could be a major health risk.

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