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Displaying 1 - 10 of 11 results.

Evaluation of rodent control to fight Lassa fever based on field data and mathematical modelling

This resource aims to to assess the efficacy of rodent control by performing a 4-year field experiment in rural Upper Guinea, and developing a mathematical model to simulate different control strategies (annual density control, continuous density control, and rodent vaccination).

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Diversity and dynamics in a community of small mammals in coastal Guinea, West Africa

This resource investigated three villages in high endemic zones of Lassa fever in Guinea and presents the biodeiversity of the small mammal community identified through standardized trapping in houses, cultivations and forest.

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Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. The study highlights that further research is necessary to identify the mechanism and the epidemiology of LF-induced SNHL.

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Rodent control to fight Lassa fever: Evaluation and lessons learned from a 4-year study in Upper Guinea

This paper performed a 4 year intervention based on chemical rodent control, utilizing anticoagulant rodenticides in 3 villages and evaluating the rodent abundance before and after treatment. They found that chemical treatment provides an effective tool to control local rodent populations. Based on these findings and the acceptability of rodent control activities at community level, the authors aim to promote, in coordination with health and agricultural authorities, a more holistic approach, including rodent trapping and poisoning, environmental hygiene, personal hygiene, house repairs and rodent-proof storage.

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Dealing with the unseen: Ffear and stigma in Lassa fever

This poster reports on research carried out with patients and caregivers at Irrua hospital.  It shows how many patients feared telling their family members that they were infected with Lassa Fever, and some were rejected by their family who refused to care for them.

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Understanding the cryptic nature of Lassa fever in West Africa

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden.

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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: The case of Lassa fever

The authors present the results of a modelling approach, using published data from outbreak and patients to Kenema governmental Hospital in Sierra Leone. They estimate the likely contribution to human to human transmission. They shed light on the need to better assess the human to human transmission.

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Fluctuation of abundance and Lassa virus prevalence in Mastomys Natalensis in Guinea, West Africa

This study investigates the link between the ecology of the M. Natalensis and the incidence of Lassa fever in human cases in Guinea. They found that the risk for Lassa virus transmission was present in both rainy and dry season; however the risk increased in the dry season because of the possibility of encountering rodent excreta in the houses.

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Movement patterns of small rodents in Lassa fever-endemic villages in Guinea

The authors investigate in this study the spatial behaviour of M. Natalensis in Upper Guinea. They use to experiments: capture-mark-recapture studies and Rhodamine B. Their findings showed that M.Natalensis moves between houses and proximate fields. This is an important information for rodent control activities that need to be extended from indoors to fields.

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Hunting of peridomestic rodents and consumption of their meat as possible risk factors for rodent-to-human transmission of Lassa virus in the Republic of Guinea

This study comparing two regions in Guinea, Pita and Gueckedou, observed three major risks for Lassa virus transmission: rodent infestation, uncovered food and hunting of peridomestic rodents as protein source. Hunting and preparation of rodents was identify as a specific risk, however more research is needed to ascertain the age and sex-specific risk factors, sociocultural and economical leading to rodent consumption.

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