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Displaying 1 - 7 of 7 results.

Lassa Fever: a rodent-human interaction

This resource examines the sites of interactions between humans and the multimammate mouse, Mastomys natalensis. It presents findings such as new arenaviruses in other African rodents and in snakes, that  argue preferably toward the host-switching concept. The recent emergence in Sierra Leone, the absence of virus positive Mastomys between the two endemic zones and poor virus diversity in the Mano River area also point in the direction of a unique import of Lassa virus from Nigeria to Sierra Leone during the 19th century. This resource also discusses the hypothesis of human displacements through the Atlantic slave trade and its abolition in 1807.

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Diversity and dynamics in a community of small mammals in coastal Guinea, West Africa

This resource investigated three villages in high endemic zones of Lassa fever in Guinea and presents the biodeiversity of the small mammal community identified through standardized trapping in houses, cultivations and forest.

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Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. The study highlights that further research is necessary to identify the mechanism and the epidemiology of LF-induced SNHL.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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Dealing with the unseen: Ffear and stigma in Lassa fever

This poster reports on research carried out with patients and caregivers at Irrua hospital.  It shows how many patients feared telling their family members that they were infected with Lassa Fever, and some were rejected by their family who refused to care for them.

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Fluctuation of abundance and Lassa virus prevalence in Mastomys Natalensis in Guinea, West Africa

This study investigates the link between the ecology of the M. Natalensis and the incidence of Lassa fever in human cases in Guinea. They found that the risk for Lassa virus transmission was present in both rainy and dry season; however the risk increased in the dry season because of the possibility of encountering rodent excreta in the houses.

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Lassa fever: Epidemiology, clinical features, and social consequences

This resource describes the epidemiology of Lassa fever and its vector, as well as the clinical course and management of the disease. It then reports on current treatment efforts, surveillance and disease control before presenting community perspectives through a knowledge, attitude and practice survey and a qualitative study.  

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