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Displaying 1 - 10 of 37 results.

Lassa Fever: a rodent-human interaction

This resource examines the sites of interactions between humans and the multimammate mouse, Mastomys natalensis. It presents findings such as new arenaviruses in other African rodents and in snakes, that  argue preferably toward the host-switching concept. The recent emergence in Sierra Leone, the absence of virus positive Mastomys between the two endemic zones and poor virus diversity in the Mano River area also point in the direction of a unique import of Lassa virus from Nigeria to Sierra Leone during the 19th century. This resource also discusses the hypothesis of human displacements through the Atlantic slave trade and its abolition in 1807.

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Diversity and dynamics in a community of small mammals in coastal Guinea, West Africa

This resource investigated three villages in high endemic zones of Lassa fever in Guinea and presents the biodeiversity of the small mammal community identified through standardized trapping in houses, cultivations and forest.

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Forecasting rodent outbreaks in Africa: an ecological basis for Mastomys control in Tanzania

This study collected rainfall data preceding historical outbreaks of Mastomys rats in East Africa in order to test the hypothesis that such outbreaks occur after long dry periods. It found that rodent outbreaks were generally not preceded by long dry period and the population dynamics of Mastomys natalensis rats in Tanzania are significantly affected by the distribution of rainfall during the rainy season.

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Epidemic preparedness and management: A guide on Lassa fever outbreak preparedness plan

This resource discusses the principles of epidemic management using an emergency operating center model, reviews the epidemiology of Lassa fever in Nigeria, and provides guidance on what is expected to be done in preparing for an epidemic of the disease at health facilities and local and state government levels in line with the Integrated Disease Surveillance and Response strategy.

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Knowledge and application of infectious diseases control measures among primary care workers in Nigeria: The Lassa fever example

This resource investigates the knowledge and practice of Lassa fever control among primary care health workers. The study was a cross-sectional survey of health workers in 34 primary care centres in Esan West and Esan Central Local Government Areas.

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Epidemics and related cultural factors for Ebola hemorrhagic fever in Gabon

This resource collected information about Ebola hemorrhagic fever (EHF) epidemics from the Gabon Ministry of Health, district hospitals and other facilities and conducted in-depth interviews with 20 villagers and 2 traditional healers in the village where the third epidemic occurred. This study suggests that cultural factors might be very crucial to EHF outbreaks in developing countries. Quick intervention with health education is needed to disseminate appropriate knowledge and persuade people that traditional practices could carry a high risk of infection

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Review of cases of nosocomial Lassa fever in Nigeria: The high price of poor medical practice

This resource reviewed medical records in hospitals and clinics in rural and urban areas of Imo State, Nigeria, and reports on its investigation into two hospital outbreaks. In this study, patients with presumed and laboratory confirmed Lassa fever were identified and contracts traced. Hospital staff, patients, and local residents were questioned, records were carefully reviewed, and serum samples were taken. Serum samples were assayed for antibody specific to Lassa virus, and isolates of Lassa virus were obtained.

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A hospital epidemic of Lassa fever in Zorzor, Liberia

This resource describes the epidemic of Lassa fever at a missionary hospital in Zorzor, Liberia, and clinical features and diagnostics. It then goes on to examine both the index case and the subsequent search for further cases. 

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Nigeria Centre for Disease Control (NCDC): Contact tracing, national guidelines for Lassa fever case management

The national guidelines for contact tracing and case management of Lassa fever as outlined by the Nigeria Centre for Disease Control.

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Lassa Virus Hemorrhagic Fever in Benin in 2014 in an Ebola Context: An Epidemic Revealing the Weakness of the Health System

This resource aims to understand the social conditions of the outbreak and evolution of the Lassa haemorrhagic fever epidemic in Benin, 2014, and the technical, political and institutional processes of its management by the state and international alert network and health response. It reports on the results of a qualitative survey conducted at several sites: at the Ministry of Health in Cotonou, in the health services (including the Saint-Jean de Dieu Hospital in Tanguiéta in the north of the country), and in the families of the geographical area of ​​the epidemic.

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