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Nigeria Centre for Disease Control (NCDC): Contact tracing, national guidelines for Lassa fever case management

The national guidelines for contact tracing and case management of Lassa fever as outlined by the Nigeria Centre for Disease Control.

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Organizing the donation of convalescent plasma for a therapeutic clinical trial on Ebola Virus Disease: The experience in Guinea

This resource reports on the successful organization of donor mobilization and plasma collection as part of the Ebola-Tx clinical trial from November 2014 to July 2015 in Conakry, Guinea, the challenges they faced, and efforts made to address these.

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Social consequences of Ebola containment measures in Liberia

This study of quarantine during the Ebola epidemic in Liberia also shows that state-enforced quarantine, with a mandatory prohibition of movement, raised condemnation, strengthened stigmatization and created serious socio-economic distress.

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The politics of fear: Médecins Sans Frontières and the West African Ebola epidemic

This book provides a primary documentary resource for recounting and learning from the Ebola epidemic. Comprising eleven topic-based chapters and four eyewitness vignettes from both MSF- and non-MSF-affiliated contributors, it aims to provide a politically agnostic account of the defining health event of the 21st century so far to inform current opinions and future responses.

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Understanding the cryptic nature of Lassa fever in West Africa

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden.

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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: The case of Lassa fever

The authors present the results of a modelling approach, using published data from outbreak and patients to Kenema governmental Hospital in Sierra Leone. They estimate the likely contribution to human to human transmission. They shed light on the need to better assess the human to human transmission.

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Impact of Lassa fever on the practice and consumption of stored food by University of Benin community, in Benin City, Nigeria

The aim of the study is to determine the impact of Lassa fever on the consumption of processed snacks and food storage practices in University of Benin campuses. They found that the that majority discard their snacks when contaminated while some remove the contaminated portions and consume remaining part which could be a major health risk.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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'He is now like a brother, I can even give him some blood': Relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia

This paper explores social relations within the ‘trial community’ (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, it looks at processes of mediation between scientific project and study population, between formal ethics, local ethical debates, and everyday practice.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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