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Displaying 11 - 20 of 33 results.

Power, fairness and trust : understanding and engaging with vaccine trial participants and communities in the setting up the EVOVAC-Salone vaccine trial in Sierra Leone

In this article the authors discuss the implementation of an Ebola vaccine trial in Kambia district in Sierra Leone during and after the epidemic. They analyze the role of social science research for the development of community engagement strategies. The authors give special attention to the analysis of rumours as source of information and explanation about resistance rooted in a much deeper sociopolitical context.

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Use of protective gear and the occurrence of occupational Marburg hemorrhagic fever in health workers from Watsa health zone, Democratic Republic of the Congo

This paper shows how health workers used PPE in an outbreak of Marburg Virus in DRC.  The findings show that HWs protected themselves better during invasive procedures (injections, venepuncture, and surgery) than during noninvasive procedures, but the overall level of protection in the hospital remained insufficient, particularly outside of isolation wards. The reasons for inconsistent use of protective gear included insufficient availability of the gear, adherence to non-biomedical explanatory models of the origin of disease, and peer bonding with sick colleagues.

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Understanding the cryptic nature of Lassa fever in West Africa

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden.

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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: The case of Lassa fever

The authors present the results of a modelling approach, using published data from outbreak and patients to Kenema governmental Hospital in Sierra Leone. They estimate the likely contribution to human to human transmission. They shed light on the need to better assess the human to human transmission.

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Shadowlands and dark corners: An anthropology of light and zoonosis

This paper outlines the importance of the house construction and the light for the human and rodent interactions in Upper Guinea (Guinea). To address this interspecies entanglements it is necessary to have in mind how darkness created by furniture and the house design can expand the activity of the animal and the persistence of virus in surfaces. It also highlights the difficulty to localize the trapping of small rodents by kids.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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U.S. Centre for Disease Control (CDC): Lassa fever

Further information from the U.S. CDC in both English and French about the transmission, prevention, diagnosis and treatment of Lassa fever.

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U.S Centre for Disease Control (CDC): Ebola hemorrhagic fever information packet

This resource provides a fact sheet for Ebola as well as a case count and location list for April 9th, 2010.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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The use of Lassa fever convalescent plasma in Nigeria

This resource describes the use of Lassa fever convalescent plasma amongst patients at hospitals in Jos and Vom, Nigeria as a potential therapy. 

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