Skip to main content
Care

Clinical research 

Clinical research has been accelerated since the export of Lassa cases to Germany and Sweden in 2016 and the outbreaks declared in Republic of Benin (2014, 2016, 2017, 2018), and with recurrent outbreaks Guinea, Sierra Leone and Liberia; as well as the 2018 epidemic in Nigeria which affected 21 States with a total of 1878 suspected cases, of which 420 were confirmed positive.  At the same time, the lessons learned during the West African Ebola outbreak, when the global community was unable to deploy vaccines until the epidemic was in its tail despite having had a number of vaccine candidates in the pipeline, galvanized the global health community. The WHO has developed a research and development roadmap for Lassa fever. CEPI, a global partnership which aims to develop vaccines against emerging infectious diseases, recently began preparation of clinical trial sites for Lassa fever in different West African Countries.

Resources

WHO: 1996 - Lassa fever in Sierra Leone - update 2

The conclusion of the WHO support mission is that a major epidemic of Lassa Fever has occurred in Kailahun and Kenema Districts and is continuing as unusually large numbers of severely ill patients are still being admitted to hospital, with a large number of deaths still occurring.

Read more
Learn more about this resource.

WHO: Lassa fever research and development (R&D) roadmap

This resource provides a framework for identifying the vision, underpinning strategic goals, and prioritizing areas and activities for accelerating the collaborative development of medical countermeasures.

Read more
Learn more about this resource.

When experiments travel: Clinical trials and the global search for human subjects

This book aims to challenge conventional understandings of the ethics and politics of transnational science and change the way we think about global medicine and the new infrastructures of our lives. It explores the clinical trials industry through both an economic and cultural lens to examine the ways commercial medical science is currently being integrated into local health systems.

Read more
Learn more about this resource.

Ethics and the ethnography of medical research in Africa

This resource outlines two emerging approaches to medical ethics, and summarises each of seven papers selected from the conference for inclusion in this special issue on ethics and ethnography, and finally highlights two areas of lively debate at the conference itself: the appropriateness and value of ethics guidelines and review boards for medical research; and the ethical review of social science research.

Read more
Learn more about this resource.

'Transport to where?': Reflections on the problem of value and time à propos an awkward practice in medical research

This resource examines the gap between the bioethics aversion to value transfers in clinical trials, and research participants' and researchers' expectations of these. It focuses upon so-called 'transport reimbursement' (TR): monetary payments to participants that are framed as mere refund of transport expenses, but which are of considerable value to recipients.

Read more
Learn more about this resource.